Another Beneficial Enzyme, Lumbrokinase
Update March 11th 2025 - added references and commentary
I'd like to share a personal experience that happened to me last week, that I believe had a profound impact on my health.
I'm a big believer in nutritional supplements. I have seen some remarkable benefits from them. First beginning with Magnesium, solving my back issues I've dealt with for ages. My back used to go out like clockwork, once or twice a year, like Ralph Kramden on the Honeymooners. Or for the younger generation,.. like Charlie Harper suffered with, in one episode on Two and a Half Men. That was a funny episode. With Alan crying, “There is no justice. This is a justice free zone... Justice? Sorry, fresh out.” But I digress… Who knew it was a simple nutrient deficiency all those years? Certainly not my neurologist who prescribed Gabapentin, making me dizzy. BTW, my back has not gone out in ten plus years since taking Mg. Truly incredible.
Then heartburn and related stomach issues completely disappearing with probiotics and digestive enzymes. And NAC, Quercetin and vitamin C helping with my COPD. It's been over ten years since being diagnosed, and still haven't had any need for any medication or supplemental oxygen.
These are just some of the benefits I have seen. Your results may differ. I should add, I was not a sickly individual. I taught karate and was very athletic. But as I got older, late 50’s, I got slammed with health issues. But even so, most of us are in need of some help. As was the case with my back seizing occasionally for two or three decades. Numerous studies reveal, nutrient deficiencies and insufficiencies exist even among the majority of the population (D3, Mk-7, Mg). Those creeping up in age have other nutrient concerns. These include Zinc, Glutathione (NAC), CoQ-10, probiotics, digestive enzymes and other such nutrients found in short supply as we age.
Well a couple of weeks ago I added another supplement to my regiment. I recently added Nattokinase to my arsenal, in the hope it might help combat atherosclerosis, inhibit and break up blood clots, and possibly degrade spike proteins that may exist. Now I haven't really noticed if I am experiencing any of these benefits. I would think that would be hard to tell anyway, without some testing. Such as checking lipid levels (cholesterol) through a simple blood test. If it's lowering bad cholesterol, I know it is probably clearing plaque in my arteries as well. As gathered from two studies I showed previously (not here of course as this is my first post) looking at atherosclerosis and hyperlipidemia....
Clinical study on the effect of nattokinase on carotid artery atherosclerosis and hyperlipidemia (China 2017)
It seems obvious to me, if it's benefitting hyperlipidemia, then it's also having benefits for atherosclerosis as well. The results in those two studies seemed to go hand in hand.
Just an aside,.. With Nattokinase, I would take the effective dose seen in these two human studies,… 6,000 FU’s (300mg) and above. It should also be noted, those studies were done by the same authors who have ties to a pharmaceutical company that produces Nattokinase. Unlike here, where Big Pharma has no interest in low cost, effective enzymes. They wouldn’t want it to cut into their blood thinning medications and statins. Statins are their number one biggest seller. But getting back to those studies,.. being they were able to reproduce very similar results in two studies, 5 years apart, strengthens the evidence greatly. Showing it wasn’t a fluke, or a result by chance.
Nattokinase is not the only enzyme to have shown benefits for heart health. There are two other systemic enzymes in the same class as Nattokinase. They are Serrapeptase and Lumbrokinase. All are considered proteolytic enzymes. Enzymes that break down proteins...
Comparing Serrapeptase, Nattokinase and Lumbrokinase: An Evidence-Based Guide - DowneLink (2024)
Nattokinase, Serrapeptase, Lumbrokinase: Your Expert Guide on Powerful Systemic Enzymes - DowneLink (2024)
All have similar benefits, with a few differences. Serrapeptase is more known for reducing pain and inflammation. While the other two are a bit more beneficial for heart health and the cardiovascular system. Serrapeptase and Nattokinase have been studied more extensively than Lumbrokinase. But on all accounts that I have seen, whether from anecdotal reports or research, Lumbrokinase has performed head and shoulders above the other two. Being much more powerful in what it does. 30 times more powerful than Nattokinase and 300 times more than Serrapeptase.
Lumbrokinase for Heart Health - The Medical Advisor (2023)
So on that basis, I gave it a try. There are many manufactures that bottle Nattokinase and Serrapeptase together, so I see no harm in taking Lumbrokinase with Nattokinase. But to play it safe, I take them separately at different times during the day or rotate them every other day. Enzymes in general are considered very safe. But with what they do in thinning your blood, you should not be taking them with medications that do the same, including aspirin.
When I started taking Nattokinase, I saw no direct benefits. Doesn't mean there aren't any, just haven't noticed them. But when I recently started taking Lumbrokinase, something very dramatic happened. I stopped going to the bathroom 3 or 4 times a night. For the past few days, I have actually slept through the entire night, without having to get up once to relieve myself. And that for me,... is an insane development.
I know my prostate is enlarged. It is quite common with all men advancing in age. And I have tried quite a few supplements to help with this condition, with very limited success. I have tried DIM, Saw Palmetto and Pumpkin Seed Oil. All are supposed to be anti-inflammatory, but only real pumpkin seed oil from Austria had some benefits for me. Although, it had no real effect on my frequent nighttime trips to the bathroom. I had been dealing with this frequency for the better part of ten years, if not longer.
I remember years ago, a roommate and old friend of mine, having this problem when we shared an apartment. And I couldn't understand why he had to go all night long. Then I got older, and it happened to me.
This new development is just amazing. They say uninterrupted sleep is probably the best thing for your health. More so than eating a healthy diet or even exercise. Your body does amazing things while you sleep. Mainly involved in restoration. Your GI tract actually stops digestion, in order to transfer resources to healing processes. That's why we feel like crap when we don't get a good night's sleep. I haven't had a real good night's sleep in ten years! I have no problem getting to sleep, but getting up 3 or 4 times a night, can't be as good as sleeping straight through the night.
I can't tell you how flabbergasted I was over this. After all this time, trying to find something that would help, then taking something for completely different reasons altogether and to have this happen,.. is just amazing. There is no doubt Lumbrokinase is a very powerful anti-inflammatory. Because I believe that is what an enlarged prostate is all about. Even though the science is not clear on this. The general consensus is that it is hormonal. Whatever it is,... Lumbrokinase, or maybe combined with Nattokinase has really made an incredible difference. Who knows what other benefits it's having on my health. It does cost a bit more than Nattokinase, but I just love this remarkable benefit I am seeing.
It might be too good to be true. I have only experienced this benefit for 3 days so far. So I hope it continues.... Magnesium had a similar benefit in improving sleep when I first started taking it, but has since worn off. I hope this is a lasting benefit.
Edit:... It seems this was only a temporary benefit/effect similar to first taking magnesium. I guess my body adjusted to the enzymes. It's weird how this happens. How some effects wear off. It's like the dozen or so arthritic medications that people keep on changing, as the benefits of each med wanes over time. But as more time has passed, I have noticed there is still some reduction in frequency. It's not as dramatic as not having to get up at all, but on average, the urgency has decreased somewhat.
But just as magnesium has resolved my back issues I had for ages, I'm sure Lumbrokinase's other benefits for heart health will be long lasting. And best of all, it is another very safe supplement. Suggested use is usually 40 mg/day. Here in this study, they were given 1,470 mg/day for 14 days with no ill effects. That's 35 times the recommended daily dose....
The Safety and Tolerability of Lumbrokinase in Healthy Adult Subjects (Indonesia 2016)
Lumbrokinase is used by some doctors to treat Lyme disease. It has the power to break down the biofilm of bacteria that causes Lyme disease. In China, it is an official medicinal used in many hospitals.
“Lumbrokinase is used as an oral supplement to support and maintain healthy cardiovascular function, and to treat cardiovascular diseases in clinical [practice] for more than 10 years." Lumbrokinase Protects Against Myocardial Ischemia-Reperfusion Injury (Taiwan 2018)
"Lumbrokinase exists as a complex of six serine protease isoforms. Each isoform has different molecular weights with a variety in fibrinolytic activity. It has a dual mechanism in clot degradation: acts on fibrin directly and activates plasminogen and converts it into plasmin, which subsequently induce plasmin-based clot dissolution." Role of Fibrinolytic Enzymes in Anti-Thrombosis Therapy (China 2021)
"To explore the clinical efficacy and safety of lumbrokinase in the treatment of acute and moderate pulmonary thromboembolism…… The clinical efficacy of the lumbrokinase group was better than that in the control group." Effect of lumbrokinase on patients with acute and moderate risk pulmonary thromboembolism (China 2017)
Most of this research comes from the far east. And as mentioned, it has been used in hospitals there for more than ten years. We in the west, are just catching up on its potential benefits. Below is a PDF from the FLCCC entitled,.. All About Lumbrokinase. But in reality, it is very sparse in information, which illustrates my point on the west needing to catch up…
But here is a Cardiologist, Dr. James Roberts, MD, FACC, in practice for 40 years in Ohio, specializing in integrative cardiology. He has given many lectures online concerning heart health. In this one, he goes over the benefits, history and mechanisms of Lumbrokinase in great detail. Also supplying results from hospital studies showing a very significant reduction in arterial plague. This presentation took place before the pandemic, so it’s all about its safe use and improving cardiovascular health. Especially in those dealing with Metabolic syndrome. That is a cluster of conditions that increase the risk of heart disease, stroke, and type 2 diabetes. Which is generally some combination of obesity, hypertension, high cholesterol, and/or insulin resistance.
Proteolytic enzymes Nattokinase and Lumbrokinase have become popular supplements for Long COVID sufferers, reportedly benefiting over 60% of those who try them. Clotting within the capillaries, leads to impaired tissue oxygenation. Explaining the persistent fatigue, brain fog, cognitive impairment, and shortness of breath, that are the hallmarks of Long COVID. And with the spike’s known persistence, and its triggering of clot formation, it makes sense these enzymes would be helpful.
“In as much as Long COVID is a medical condition where amyloid fibrin clots form, it is tempting to speculate that lumbrokinase, serving as an anticoagulant and amyloid-reducing agent, may be the answer we are looking for. And with respect to safety, lumbrokinase has safety written all over it. Indeed,… with use of Lumbrokinase, “no internal bleeding has been reported.” (Munawar et al., 2021) “So it is a safe drug.” (Cao et al., 2013)” Lumbrokinase for Long COVID.pdf (2022)
Update: In later articles, I go over other promising treatments for these severely debilitating conditions (vaxxed injured & PASC)…
Additional Info on Novel Treatment for Long-Haulers and Vaccine Injured
Nicotine Might Help with Brain Fog and other Long-Term Symptoms
In Summation,… Lumbrokinase could be beneficial in helping us detox the spike protein. We’ve all been exposed to it,... whether through viral infection, vaccination, shedding, or even the meat we eat. Shedding is real. Don’t let anyone tell you otherwise. And exposes even the unvaccinated to the toxic spike (more on this in a future article). Lumbro is a powerful combo of 6 enzymes in one. All of which have fibrinolytic activity to degrade proteins. 30 times more powerful than Nattokinase. And the spike is a viral protein. It also breaks down blood clots maintaining a haemostatic balance,.. improving blood flow in a very safe manner that drugs cannot match.
In this Substack, I will express the research I have done, since I was first diagnosed with stage 2 cancer a little more than ten years ago. All in my quest for improved wellness. It has served me very well up to now, especially during the pandemic.
Stay safe and be well…
Just thought I would tell you that I read an article recently about nebulized glutathione and how it is a remarkable treatment for COPD. I wish I could remember where I read it. I know you said your COPD doesn’t require medication or supplemental oxygen, but it may be something to keep in mind.
Thanks for the information!
Thank you for all the information you share to help others 🫶