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Moro Balakrishnan's avatar

Excellent real life story this. My compliments to ohbaby. There is no doubt about the prophylactic potential of IVM in Covid. The highly populous state of UP ( and very backward in social indices) had not resorted to the large scale prophylactic use of IVM during the Delta burst in April/May 2021, the cases and hence deaths would have reached sky high. I am from India and has followed this Covid story everywhere closely. It is also correct not many states followed the Ivermectin protocol seriously. However, in the second half of 2021, cases, hospitalisations and deaths began dropping dramatically. Yes, by mid 2021 only about 15%of the 1.3 billion population had been double vaccinated ( Astra Zeneca one, made in the country) and by end 2021 this rose to about 80% of the population. Honestly, I don’t ascribe the dramatic fall in numbers in the second half of 2021 to this. Doctors, hundreds of thousands of them, who were aware of the value of early treatment protocols with standard URT medications ( Azithromycin, Montelukast, Levocetrizine and the like) massively took to this protocol in the mid months of 2021 at the height of the delta wave. I will explain later how this cut down the spread drastically. This protocol became a standard outpatient treatment, individual viral load build up came down, and with it the chance of the severe second phase ( auto immune) occurring around the 8th day disappeared. Ivermectin was used in this protocol by many doctors but not massively. It did provide its therapeutic value, but it was not a compulsory in the multi drug repurposed protocol very widely accepted. So the role of this protocol should not be gainsaid.

The vaccination did not prevent a country wide Omicron burst in early 2022, but this repurposed protocol did. In Jan 2022, I went for this type of protocol on my own ( I am not a doctor, but an old PhD organic chemist) with telling results. If interested I can put up a list of dozen odd drugs that I collected from about 15 prescriptions. The wave disappeared as quickly as it came. Since mid 2022, we had literally stopped talking about Covid. Around that time vaccinations also came to a halt, with only about 15% taking a third shot. People and in turn the govt also gave up on repeat vaccinations.

Ivermectin was an off label antiviral, but most of the other drugs in the protocol too were off label anti viral, by virtue of their some shared chemical structure features. They were all basically belonging to a group/classification called “Cationic Amphiphilic Drugs” (CADs), long known to be anti viral despite their main indications. In Omicron wave, this early treatment became almost institutional. When the first infected in the family is treated early ( on the basis of symptoms), with this multi drug prescriptions, he/she recovers quickly without reaching a large viral load build up. The viral load he carries at the max is not enough to infect others in the family. The family is spared. And the bonus. They get passive exposure to the virus giving them the preferred natural immunity. Multiply this over thousands of households in a community - there is no spread and every one has acquired the herd immunity. The virus retires. Precisely what happened here between mid 2021 and mid 2022. We never used the Paxlovids and Molnupiravirs. Our outpatient treatment, including two consultations, did not cost more than 30 dollars. The poor had this for free in the community health centres and hospitals.

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